When someone says “Midwest,” your first thought might be cornfields, casseroles, and college football. But this heartland of America offers so much more, especially when it comes to quality education. The best colleges in the Midwest combine world-class academics, unbeatable campus vibes, and a healthy dose of school spirit.
If you’re dreaming of groundbreaking research or a cozy campus where everyone knows your name, these Midwest schools have something for everyone. Let’s break it down and find your perfect fit.
- University of Chicago
- Northwestern University
- University of Michigan
- Washington University in St. Louis
- University of Notre Dame
- Purdue University
- University of Illinois Urbana-Champaign
- University of Wisconsin–Madison
- How to Choose the Best Midwest University for You
- Frequently Asked Questions
- Takeaways
1. University of Chicago
Location: Chicago, Illinois
Acceptance rate: 4.5%
The University of Chicago is where intellectuals thrive and the fun goes to… read a book. Kidding—sort of. This is the place for you if phrases like “core curriculum” and “rigorous debate” light you up. Their core curriculum will have you reading Plato, solving quantum mechanics, and asking existential questions by midterms.
The University of Chicago doesn’t just accept anyone. UChicago is one of the most selective schools in the world, and the numbers don’t lie. For the Class of 2028, UChicago received 43,612 applications and admitted just 1,955 students.
This academic powerhouse has a middle 50% SAT range of 1510–1560 and ACT range of 34–35. It’s #11 in the U.S. News & World Report’s national rankings and has more research centers than some states have Starbucks. No, really: UChicago boasts over 140 research centers and institutes, which makes it a research giant among the best colleges in the Midwest.
The Hyde Park location offers proximity to downtown Chicago without all the chaos. And if you’re into economics, this is where legends like Milton Friedman got their start. UChicago is a lifestyle of relentless questioning and occasional deep-dish pizza.
2. Northwestern University
Location: Evanston, Illinois
Acceptance rate: 7.5%
Located just a 30-minute train ride from Chicago, Northwestern University offers the best of both worlds: a quaint college town vibe and access to a bustling metropolis. It’s no surprise that Northwestern consistently ranks as one of the best colleges in the Midwest.
Good news for those of you who cringe at the thought of standardized tests: Northwestern has been test-optional since 2020, and they’re keeping it that way for students applying for fall 2025. This means you can focus on showing off your personality, extracurriculars, and essays without worrying about whether your SAT or ACT scores will cut it.
Because of this policy, Northwestern hasn’t published testing data for the Class of 2028. Their message is clear: you’re more than just a number. This flexibility, combined with its stellar academics, cements Northwestern’s reputation as one of the best colleges in the Midwest.
Ranked #6 in the nation by the U.S. News & World Report, it’s home to the world-famous Medill School of Journalism and one of the most connected alumni networks. Oh, and let’s not forget its student theater scene. Meghan Markle was once here learning her craft before royal life came calling.
For anyone looking for a top-tier education with a side of stunning lake views, Northwestern is easily among the best colleges in the Midwest.
3. University of Michigan
Location: Ann Arbor, Michigan
Acceptance rate: 17.9%
The University of Michigan is where “Go Blue” is a lifestyle. This school is big, bold, and brimming with opportunities. From tackling complex engineering problems at one of the nation’s top programs to cheering on the Wolverines at the Big House (the largest stadium in the U.S.), UMich offers a little bit of everything and firmly holds its place as one of the best colleges in the Midwest.
For the most recent stats, the acceptance rate was 17.9%, with 87,632 total applications and 15,722 students admitted. The average GPA? A solid 3.76. SAT scores averaged 1346, and ACT scores hit 30. These stats scream competitive but not impossible, perfect for students who love a good challenge.
UMich is ranked #21 in the country, which further secures its place among the best colleges in the Midwest. Ann Arbor is also consistently rated one of the best college towns in America, where you can grab artisanal coffee, watch indie films, and lose yourself in bookshops. At UMich, academics are tough, the school spirit is contagious, and the opportunities are endless.
4. Washington University in St. Louis
Location: St. Louis, Missouri
Acceptance rate: 12.1%
Washington University in St. Louis is for the overachievers who still want to have a life. Tied with UMich at the #21 spot nationally, it’s consistently ranked as one of the best colleges in the Midwest.
Known for being academically rigorous yet warm and welcoming, it’s a favorite among students who want top-tier academics without sacrificing balance. Average SAT scores are between 1500–1570, with ACT scores in the 33–35 range.
If you’re gunning for med school, WashU is basically your golden ticket. More than just being known for its pre-med and healthcare programs, its National Institutes of Health (NIH) research funding portfolio is the second largest among U.S. medical schools and has grown a staggering 56% in the last seven years.
For students interested in cutting-edge research and unmatched opportunities, it’s easy to see why WashU is considered one of the best colleges in the Midwest, especially for those interested in the medical field.
The campus itself is something out of a brochure—seriously, it’s that pretty. And when you’re not on campus, you’ve got St. Louis to explore. Here’s a pro tip: the city’s toasted ravioli is a must-try, and Forest Park offers countless opportunities for Instagram-worthy moments.
5. University of Notre Dame
Location: Notre Dame, Indiana
Acceptance rate: 11.1%
The University of Notre Dame is tradition central and a staple among the best colleges in the Midwest. If you’re into iconic landmarks like the Golden Dome or religious history, this Catholic university is for you. But don’t let its reverence fool you: Notre Dame is all about forward-thinking education.
For the Class of 2028, the Fighting Irish broke yet another record, with 29,943 people applying, which is a 6% jump from the 28,353 applicants in the previous cycle. With all those dreamers vying for a spot, the acceptance rate hit a record low of 11.1%, down from 11.9% the year before.
Notre Dame’s acceptance rate has been shrinking year by year, almost like it’s on a diet. Let’s just say, getting in here is no small feat. The Class of 2028 scored an average SAT range of 1470–1540 and ACT scores between 33–35. So yes, you’ll probably need a lucky four-leaf clover to get in.
Ranked #18 nationally, Notre Dame is famous for its standout programs in business, law, and liberal arts, which help solidify its place among the best colleges in the Midwest.
But let’s talk about the campus: it’s iconic, from the Golden Dome shimmering in the sunlight to Touchdown Jesus watching over you as you hustle to class. This place practically screams, “You’ve made it.”
And then there’s the football. Oh, the football. Game days at Notre Dame are a religion unto themselves. Think roaring crowds, marching bands shaking the ground, and the kind of energy that could power the entire Midwest.
If you’re ready to balance rigorous academics with unforgettable experiences, and maybe even chant a few fight songs along the way, Notre Dame is one of the best colleges in the Midwest that can offer it all. Just be prepared to cry a little when you leave; it’s that kind of place.
6. Purdue University
Location: West Lafayette, Indiana
Acceptance rate: 49.8%
Welcome to Purdue, where innovation is practically a sport and astronauts are practically alumni mascots (yes, Neil Armstrong is one of them). For the Class of 2028, Purdue received 78,526 applications and admitted 49.8% of them. The middle 50% of admitted students had GPAs ranging from 3.62 to 4.00, SAT scores between 1210 and 1470, and ACT scores in the 27–34 range.
Ranked #18 among top public schools and #3 in aerospace, aeronautical, and astronautical programs, Purdue is the dream destination for anyone looking to reach for the stars—literally. If you’re passionate about space exploration, aviation, or building the next rocket to Mars, Purdue has you covered with one of the best aerospace programs in the country.
But Purdue isn’t all rocket science and no fun. Campus life is buzzing with energy, thanks to its vibrant student organizations, iconic traditions like fountain runs, and the occasional Boilermaker Special (a train-shaped mascot) making its way around campus. And let’s not forget the giant Boilermaker statue: perfect for Instagram-worthy moments.
With its strong academic reputation and lively campus culture, Purdue anchors its place as one of the best colleges in the Midwest. So if you’re ready to take off (literally or figuratively), Purdue is the place for you.
7. University of Illinois Urbana-Champaign
Location: Urbana-Champaign, Illinois
Acceptance rate: 42.4%
Welcome to UIUC, the crown jewel of the Illinois public university system and a paradise for anyone who geeks out over innovation. If you’re dreaming of building the next tech empire, solving global food challenges, or just enjoying that sweet Midwest charm, this Big Ten powerhouse has something for you.
UIUC’s engineering programs are legendary, ranked #5 nationally. Did you know that UIUC is the alma mater of the brains behind YouTube and PayPal? UIUC also dominates in business, agriculture, and computer science. Think of it as the overachieving kid in the Midwest who’s humble enough to still share their lunch. No list of the best colleges in the Midwest would be complete without it.
For UIUC’s Class of 2028, the average ACT was 32.1 (up from 31.5 the previous year), and the average SAT was 1440 (up from 1418 in 2023). Test scores remained optional, but about 51% of the enrolling students submitted their scores. So, while test scores can help you stand out, they’re not the only way to show you’ve got what it takes to be part of the Illini family.
The campus? It’s got the perfect combo of historic charm and modern energy. Imagine sprawling green quads, iconic brick buildings, and a student union that’s always buzzing. Urbana-Champaign itself is a vibe, with farmer’s markets, live music festivals, and enough great food to keep you happily carb-loaded during finals week (don’t skip the deep-dish pizza joints).
Ranked #9 among top public schools, UIUC is where academic rigor meets school spirit. Speaking of spirit, the Illini orange and blue runs deep: tailgates, homecoming parades, and basketball games at State Farm Center will make you a lifelong fan.
So, if you’re ready to work hard, cheer harder, and maybe change the world while you’re at it, UIUC might just be your home sweet home among the best colleges in the Midwest.
8. University of Wisconsin–Madison
Location: Madison, Wisconsin
Acceptance rate: 45.2%
Ah, the University of Wisconsin–Madison, where lakeside views meet academic prestige and the cheese is as legendary as the school spirit. Known simply as “Wisconsin” or “Madison,” this school is another Big Ten powerhouse with a reputation for combining rigorous academics with a vibrant campus culture.
It comes to no surprise that UW–Madison consistently ranks among the best colleges in the Midwest. Ranked #13 among top public universities, Wisconsin is particularly renowned for its programs in business, engineering, and life sciences.
It’s also a global leader in agricultural research, which makes it perfect for anyone who wants to tackle world hunger or discover the next big sustainability breakthrough. As one of the best colleges in the Midwest, UW–Madison offers a combination of academic excellence and real-world impact.
The campus? It’s absolutely stunning. Located between Lake Mendota and Lake Monona, Madison is a postcard-worthy college town that offers the perfect combination of natural beauty and urban charm. Say hello to a flawlessly curated Instagram feed!
The Terrace at Memorial Union is the place to be, where you can sip coffee, eat brats, and soak up the view with fellow Badgers. And don’t even get us started on game days: Camp Randall Stadium comes alive with 80,000 fans jumping around (literally) to the team’s fight song.
Madison itself is consistently ranked as one of the best college towns in the U.S., thanks to its food scene, bike-friendly streets, and limitless outdoor activities. It’s a place where you can ace a biology exam in the morning, kayak on the lake in the afternoon, and cheer your lungs out at a football game by night.
This balance of academics, community, and fun makes UW–Madison a standout among the best colleges in the Midwest. So, if you’re ready to study hard, play hard, and probably eat more cheese curds than you thought humanly possible, UW–Madison is calling your name.
How to Choose the Best Midwest University for You
Here’s the deal: rankings matter when browsing through Midwest universities, but they’re not everything. Everyone has their own preferences, and lucky for you, the best colleges in the Midwest have something for everyone.
Let’s break it down step-by-step so you can make the best choice without losing sleep or overloading on caffeine.
1. Decide on size: do you want the buzz or the chill?
Are you a fan of big crowds and even bigger opportunities? The University of Michigan’s 87,000+ applicants and its epic Big House scream energy and excitement. Purdue is another juggernaut, with massive engineering programs and a campus full of innovation.
Prefer a smaller, more community-focused vibe? Notre Dame’s campus is like stepping into a family reunion, complete with football traditions that’ll make you want to sing the fight song before you’ve even been accepted. And WashU offers all the perks of a prestigious school but with a cozy, supportive atmosphere where professors might actually learn your name.
2. Location, location, location: are you a city or country mouse?
City slickers, rejoice! Northwestern University gives you access to Chicago’s buzzing metropolis while still offering lakeside tranquility. The University of Chicago brings you Hyde Park, where you can balance hardcore academics with an occasional fried steak sandwich run.
But if you’re into the classic college town experience, Wisconsin’s Madison and UIUC’s Urbana-Champaign bring you charm, green spaces, and quirky farmer’s markets. And let’s not forget Notre Dame’s serene campus: it’s a place where tradition meets tranquility (and maybe the occasional snowstorm).
3. Academics: what’s your thing?
The best colleges in the Midwest have serious bragging rights in almost every field. Want to build the next Mars rover? Purdue’s ranked #3 in aerospace engineering for a reason. Dreaming of running your own Fortune 500 company? Notre Dame’s Mendoza College of Business is ranked #7 for undergraduate business programs.
If medicine is your calling, WashU’s NIH-funded research and pre-med programs are second to none. And if philosophical debates and existential crises sound fun to you, the University of Chicago’s core curriculum will keep you up at night (in a good way).
4. School spirit: how much do you want to bleed team colors?
If the thought of cheering alongside tens of thousands of fans excites you, schools like Michigan and Wisconsin are the place to be. Picture the electric atmosphere of the Big House filled with 100,000 voices or the legendary “Jump Around” tradition at Camp Randall Stadium with 80,000 Badgers in sync.
Not a sports fan? No problem. Schools like WashU, Northwestern, and UChicago offer a more low-key but equally spirited experience. Think student-led performances, quirky traditions, and club activities that create tight-knit communities. Whether you’re waving a foam finger or debating philosophy in a campus café, Midwest schools make sure everyone finds their tribe.
5. Winter is coming: can you handle Midwest weather?
Listen, we need to talk about the cold. The Midwest doesn’t mess around. Schools like Michigan and Wisconsin will test your endurance with freezing winds and snow-covered sidewalks. But hey, nothing builds character like trekking through a snowstorm for a morning class, right?
On the bright side, Midwest winters come with cozy coffee shops, snowball fights, and a valid excuse to wear pajamas under your parka. If the Arctic vibes aren’t for you, WashU’s St. Louis campus offers slightly less frostbite and all the perks of one of the best colleges in the Midwest.
6. Trust your gut: visit the campuses.
Rankings are nice, but nothing beats actually walking around and seeing if a school feels right. At Notre Dame, you’ll experience the iconic Golden Dome and Touchdown Jesus firsthand. At Northwestern, you can soak in lakeside views that’ll make you forget you’re there to study. And don’t skip Wisconsin’s Terrace at Memorial Union—it’s a vibe.
Here’s a pro tip: wander off the tour path. Grab a coffee, talk to students who aren’t paid to hype the school, and check out the local hangouts. The best colleges in the Midwest are the ones that feel like home.
Frequently Asked Questions
1. What are the best colleges in the Midwest?
The Midwest is home to some seriously impressive schools that cater to every kind of student. If you’re into world-class academics and a bit of intellectual flair, check out the University of Chicago or Northwestern University. Prefer a mix of academics and rowdy school spirit? Michigan and Wisconsin are your go-to Big Ten powerhouses. For future doctors or engineers, WashU and Purdue are practically life goals. No matter what you’re into, the best colleges in the Midwest have you covered.
2. How do I decide which Midwest school is right for me?
Start by considering factors like size, location, academic strengths, and campus vibe. Do you prefer the bustling city life of Northwestern in Evanston or the small-town charm of Notre Dame? Are you interested in engineering (Purdue or UIUC) or liberal arts (University of Chicago)? Visiting campuses and researching each school’s programs can help you find the best colleges in the Midwest that fit your needs.
3. How important are rankings when choosing a Midwest university?
Midwest university rankings can give you a sense of a school’s academic reputation, but they’re just one piece of the puzzle. While schools like the University of Chicago and Northwestern consistently rank among the best Midwest universities, factors like campus culture, program strengths, and financial fit are just as important when making your decision.
4. What makes Midwest schools unique?
Midwest schools are known for their balance of academic rigor and a friendly, welcoming atmosphere. Whether it’s the Big Ten school spirit at Michigan and Wisconsin or the intellectual depth of UChicago, the best Midwest universities offer something for everyone. Plus, the Midwest’s combination of vibrant college towns and dynamic urban campuses guarantees a perfect setting for any student’s preferences.
Takeaways
Choosing the right school can be overwhelming, but the Midwest is packed with incredible options to suit every personality, interest, and ambition. Here’s what you need to know as you consider the best colleges in the Midwest:
- Whether you’re drawn to the academic powerhouse of the University of Chicago, the spirited game days at Michigan, or the innovation-driven culture at Purdue, the best colleges in the Midwest cater to all interests and goals.
- Love the hustle of urban living? Northwestern puts you right next to Chicago. Prefer a picturesque college town? Schools like the University of Wisconsin–Madison and Notre Dame deliver classic Midwest vibes with modern amenities, which make them standouts among Midwest schools.
- From UIUC’s engineering programs to WashU’s pre-med track, the best colleges in the Midwest are leaders in STEM, business, liberal arts, and more. There’s no shortage of academic excellence in the heartland.
- Not sure where to start? A college admissions consultant can provide personalized guidance to help you find the perfect fit and help you land a spot at one of the best colleges in the Midwest.
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